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The following proteins in
Mus musculus
appear to match your input.
Please review the list, then click 'Continue' to proceed.
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1) '10090.ENSMUSP00000107033':
- - Sorry, STRING found no proteins by this name in Mus musculus - -
2) '10090.ENSMUSP00000097515':
Sesn1 - Sestrin-1; Functions as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway through the GATOR complex. In absence of leucine, binds the GATOR subcomplex GATOR2 and prevents TORC1 signaling. Binding of leucine to SESN2 disrupts its interaction with GATOR2 thereby activating the TORC1 signaling pathway. This stress-inducible metabolic regulator may also play a role in protection against oxidative and genotoxic stresses. May positively regulate the transcription by NFE2L2 of genes involved in the response to oxidative stress by facilitating the SQSTM1-med [...]
[a.k.a. R-MMU-9639288, Pa26, ENSMUST00000041438]