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Ahr | Aryl hydrocarbon receptor; Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing [...] (805 aa) | ||||
Zrsr1 | U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1; Plays a role in splicing of the U12-type introns. Implicated also in removal of U2 introns positioned adjacent to a U12 intron. (428 aa) |