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Crx | Cone-rod homeobox protein; Transcription factor that binds and transactivates the sequence 5'-TAATC[CA]-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors. (323 aa) | ||||
Mab21l1 | Putative nucleotidyltransferase MAB21L1; Required for several aspects of embryonic development including normal development of the eye, notochord, neural tube and other organ tissues, and for embryonic turning. It is unclear whether it displays nucleotidyltransferase activity in vivo (By similarity). Binds single- stranded RNA (ssRNA) (By similarity); Belongs to the mab-21 family. (359 aa) |