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CHD1 | Chromo domain-containing protein 1; Chromatin remodeler that regulates various aspects of transcription; acts in in conjunction with Isw1b to regulate chromatin structure and maintain chromatin integrity during transcription elongation by RNAP II by preventing trans-histone exchange over coding regions; contains a chromo domain, a helicase domain and a DNA-binding domain; component of both the SAGA and SLIK complexes. (1468 aa) | ||||
GRC3 | Polynucleotide 5'-hydroxyl-kinase GRC3; Polynucleotide kinase present on rDNA; required for efficient transcription termination by RNA polymerase I; functions with Las1p in a conserved mechanism to modulate rRNA processing and ribosome biogenesis; required for cell growth; mRNA is cell-cycle regulated; Belongs to the Clp1 family. NOL9/GRC3 subfamily. (632 aa) |