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RDS2 | Regulator of drug sensitivity 2; Transcription factor involved in regulating gluconeogenesis; also involved in the regulation of glyoxylate cycle genes; member of the zinc cluster family of proteins; confers resistance to ketoconazole. (446 aa) | ||||
APN1 | DNA-(apurinic or apyrimidinic site) lyase 1; Major apurinic/apyrimidinic endonuclease; 3'-repair diesterase; involved in repair of DNA damage by oxidation and alkylating agents; also functions as a 3'-5' exonuclease to repair 7,8-dihydro-8-oxodeoxyguanosine; genetically interacts with NTG1 to maintain mitochondrial genome integrity; Belongs to the AP endonuclease 2 family. (367 aa) |