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dwg | Deformed wings (dwg) encodes an architectural chromatin protein essential for embryonic development that organizes open chromatin in regulatory regions (predominantly promoters). dwg product binding site was found in the insulator encoded by scs, and its functions include enhancer blocking, support of distant interactions and recruitment of transcription factors. (592 aa) | ||||
Cdc6 | Cell division control protein; Cdc6 (Cdc6) encodes an essential component of the pre-Replication complex (preRC) together with the origin recognition complex, the product of dup and MCM2-7 proteins. The preRC is present at all chromosomal origins of replication and is required for the initiation of DNA replication. The product of Cdc6 also functions in the co-ordination of DNA replication with mitosis, and may contribute to apoptosis and transcription; Belongs to the CDC6/cdc18 family. (662 aa) |