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dwg | Deformed wings (dwg) encodes an architectural chromatin protein essential for embryonic development that organizes open chromatin in regulatory regions (predominantly promoters). dwg product binding site was found in the insulator encoded by scs, and its functions include enhancer blocking, support of distant interactions and recruitment of transcription factors. (592 aa) | ||||
cu | Nocturnin; Phosphatase which catalyzes the conversion of NADP(+) to NAD(+) and of NADPH to NADH. Shows a small preference for NADPH over NADP(+). Because of its association with the CCR4-NOT complex, has a role in mRNA deadenylation and decay. Required at the pupal stage for proper wing morphogenesis after eclosion. [Isoform D]: In dorsal neurons, contributes to the light- mediated behavioral response; Belongs to the CCR4/nocturin family. (642 aa) |