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The following proteins in
Drosophila melanogaster
appear to match your input.
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⤓ Mapping
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1) '7227.FBpp0070483':
N - Processed neurogenic locus Notch protein; Essential signaling protein which has a major role in many developmental processes. Functions as a receptor for membrane-bound ligands Delta and Serrate to regulate cell-fate determination. Upon ligand activation, and releasing from the cell membrane, the Notch intracellular domain (NICD) forms a transcriptional activator complex with Su(H) (Suppressor of hairless) and activates genes of the E(spl) complex. Regulates oogenesis, the differentiation of the ectoderm and the development of the central and peripheral nervous system, eye, wing disk, [...]
[a.k.a. FBgn0004647, N-PA, N-PB,
7227.FBpp0070483
]
2) '7227.FBpp0070891':
Top3beta - DNA topoisomerase 3-beta; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)- enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand than undergoes passage around the unbroken strand thus removing DNA supercoils. [...]
[a.k.a. FBgn0026015, Top3beta-PB, Top3beta-PA,
7227.FBpp0070891
]