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mof | Males-absent on the first protein; Histone acetyltransferase that plays a direct role in the specific histone acetylation associated with dosage compensation as part of the MSL complex. Dosage compensation insures that males with a single X chromosome have the same amount of most X-linked gene products as females with two X chromosomes. May be directly involved in the acetylation of histone 4 at 'Lys-16' on the X chromosome of males where it is recruited by the MSL complex. As part of the NSL complex may associate with promoters of X chromosomal as well as autosomal genes and positivel [...] (827 aa) | ||||
Nup75 | Nuclear pore complex protein Nup75; Component of the nuclear pore complex (NPC) that seems to be required for NPC assembly and maintenance (By similarity). Required for nuclear import of phosphorylated Mad via importin msk. Has no role in classical nuclear localization signal (cNLS)-dependent nuclear import via importin-beta. Facilitates the interaction between Nup93 and sec13 with msk. (668 aa) |