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mof | Males-absent on the first protein; Histone acetyltransferase that plays a direct role in the specific histone acetylation associated with dosage compensation as part of the MSL complex. Dosage compensation insures that males with a single X chromosome have the same amount of most X-linked gene products as females with two X chromosomes. May be directly involved in the acetylation of histone 4 at 'Lys-16' on the X chromosome of males where it is recruited by the MSL complex. As part of the NSL complex may associate with promoters of X chromosomal as well as autosomal genes and positivel [...] (827 aa) | ||||
Nse4 | Non-SMC element 4 (Nse4) encodes a member of the EID (EP300-interacting inhibitor of differentiation) family of proteins. It is the kleisin component of the SMC5/6 protein complex. This complex is critical to genome stability, and is required for homologous DNA recombination-based processes. (290 aa) |