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pita | Pita, isoform A; Pita (pita) encodes an architectural chromatin protein essential for embryonic development that organizes open chromatin in the regulatory regions (predominantly promoters). pita product functions include enhancer blocking, support of distant interactions, protection from spreading of repressed chromatin and recruitment of transcription factors. (683 aa) | ||||
Nup98-96 | Nuclear pore complex protein Nup98-Nup96; Part of the nuclear pore complex (NPC). Required for MAD import as part of the Nup107-160 complex and required for nuclear export of Moe probably via its association with Rae1. Plays a role in nuclear mRNA export. Promotes cell antiviral response by upregulating FoxK-dependent antiviral gene transcription. In germline stem cells, involved in their maintenance and division together with the TGF-Beta and EGFR signaling pathways. In larval lymph glands, has a role in the maintenance of hematopoiesis by regulating Pvr expression. [Nuclear pore comp [...] (1960 aa) |