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Pof | Protein painting of fourth; Probable RNA-binding protein that specifically binds to the fourth chromosome and may bind an RNA that spreads the fourth chromosome. May be a reminiscence of X chromosome dosage compensation of ancestral Drosophila species in which the X and the fourth chromosomes are one single chromosome. (495 aa) | ||||
cpa | Capping protein alpha (cpa) encodes an actin-binding protein that, along with the product of cpb, binds to the fast growing ends of actin filaments to restrict the addition or loss of actin monomers. It limits the nuclear translocation of the Hippo pathway mediator encoded by yki and restricts JNK signaling. It maintains epithelial integrity and controls the balance between proliferation and apoptosis in the wing imaginal disc. It plays important roles during oogenesis, as well as maintaining neuronal homeostasis. (286 aa) |