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Pof | Protein painting of fourth; Probable RNA-binding protein that specifically binds to the fourth chromosome and may bind an RNA that spreads the fourth chromosome. May be a reminiscence of X chromosome dosage compensation of ancestral Drosophila species in which the X and the fourth chromosomes are one single chromosome. (495 aa) | ||||
UbcE2M | Nedd8-conjugating enzyme UbcE2M; Accepts the ubiquitin-like protein Nedd8 from the Uba3-APP- BP1 E1 complex and catalyzes its covalent attachment to other proteins. Required for Cul1 and Cul3 neddylation. Negatively regulates full- length ci stability and hedgehog signaling. (181 aa) |