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dre4 | FACT complex subunit spt16; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (1122 aa) | ||||
wnd | Wallenda (wnd) encodes a kinase in the mixed lineage family of MAP Kinase Kinase Kinases. Its roles include axonal injury signaling (it becomes activated in neurons after axotomy), and in regulation of the structure of presynaptic boutons. (977 aa) |