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dre4 | FACT complex subunit spt16; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (1122 aa) | ||||
Hers | Histone gene-specific epigenetic repressor in late S phase, isoform A; Transcription regulatory region sequence-specific DNA binding; chromatin binding. It is involved in the biological process described with: chromatin silencing; chromatin remodeling. (2529 aa) |