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The following proteins in
Drosophila melanogaster
appear to match your input.
Please review the list, then click 'Continue' to proceed.
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1) '7227.FBpp0073433':
Upf1 - Regulator of nonsense transcripts 1 homolog; RNA-dependent helicase and ATPase required for nonsense- mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited to mRNAs upon translation termination and undergoes a cycle of phosphorylation and dephosphorylation; its phosphorylation appears to be a key step in NMD. The formation of an Upf1-Upf2-Upf3 surveillance complex is believed to activate NMD (By similarity).
[a.k.a. FBgn0030354, Upf1-PA, Upf1-PB,
7227.FBpp0073433
]
2) '7227.FBpp0076829':
DnaJ-1 - DnaJ-like-1 (DnaJ-1) encodes a heat-shock protein co-factor that regulates and interacts with larger heat shock proteins providing client specificity. It regulates the folding of proteins whose misfolding leads to age-dependent neurodegeneration.
[a.k.a. FBgn0263106, DnaJ-1-PA, DnaJ-1-PB,
7227.FBpp0076829
]