Version:
12.0
Login
Register
Survey
STRING
STRING
Search
Download
Help
My Data
The following proteins in
Drosophila melanogaster
appear to match your input.
Please review the list, then click 'Continue' to proceed.
<- Back
⤓ Mapping
Continue ->
1) '7227.FBpp0073433':
Upf1 - Regulator of nonsense transcripts 1 homolog; RNA-dependent helicase and ATPase required for nonsense- mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited to mRNAs upon translation termination and undergoes a cycle of phosphorylation and dephosphorylation; its phosphorylation appears to be a key step in NMD. The formation of an Upf1-Upf2-Upf3 surveillance complex is believed to activate NMD (By similarity).
[a.k.a. FBgn0030354, Upf1-PA, Upf1-PB,
7227.FBpp0073433
]
2) '7227.FBpp0111630':
Snoo - Sno oncogene (Snoo) encodes a protein that belongs to the highly conserved Sno/Ski family of Smad binding proteins. It specifically binds the product of Med and switches its affinity from the products of Mad to Smox, resulting in antagonism of the product of dpp and facilitation of Activin signaling. Snoo overexpression antagonizes both pathways.
[a.k.a. FBgn0085450, Snoo-PB, Snoo-PG,
7227.FBpp0111630
]