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The following proteins in
Drosophila melanogaster
appear to match your input.
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⤓ Mapping
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1) '7227.FBpp0073433':
Upf1 - Regulator of nonsense transcripts 1 homolog; RNA-dependent helicase and ATPase required for nonsense- mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited to mRNAs upon translation termination and undergoes a cycle of phosphorylation and dephosphorylation; its phosphorylation appears to be a key step in NMD. The formation of an Upf1-Upf2-Upf3 surveillance complex is believed to activate NMD (By similarity).
[a.k.a. FBgn0030354, Upf1-PA, Upf1-PB,
7227.FBpp0073433
]
2) '7227.FBpp0297151':
ash1 - Histone-lysine N-methyltransferase ash1; Trithorax group (TrxG) protein that has histone methyltransferase activity. Specifically trimethylates 'Lys-4' of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation. TrxG proteins are generally required to maintain the transcriptionally active state of homeotic genes throughout development. Does not act as a coactivator required for transcriptional activation, but specifically prevents inappropriate Polycomb Group (PcG) silencing of homeotic genes in cells in which they must stay transcriptionally active. Belongs to t [...]
[a.k.a. FBgn0005386, ash1-PC, ash1-PB,
7227.FBpp0297151
]