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disco | Disconnected (disco) encodes a C2H2 zinc finger transcription factor involved in development of ventral appendages (e.g. legs and some mouthparts) during embryogenesis and metamorphosis. (568 aa) | ||||
Apc | APC-like, isoform A; APC-like (Apc) encodes one of two Drosophila APC family proteins. It is a key negative regulator of Wingless signaling, as a critical component of the destruction complex that phosphorylates beta-catenin and thus targets it for ubiquitination and proteasomal destruction. It is the primary family member during CNS and eye development, and functions redundantly with the product of Apc2 in adult development. (2417 aa) |