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The following proteins in
Drosophila melanogaster
appear to match your input.
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⤓ Mapping
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1) '7227.FBpp0074594':
Su(var)3-3 - Possible lysine-specific histone demethylase 1; Probable histone demethylase that specifically demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for heterochromatic gene silencing. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and tri-methylated 'Lys-4' of histone H3. May also demethylate 'Lys-9' of histone H3, Plays a role in the repression of neuronal genes; Belongs to the flavin monoamine oxidase family.
[a.k.a. FBgn0260397, Su(var)3-3-PB, Su(var)3-3-PC,
7227.FBpp0074594
]
2) '7227.FBpp0290493':
Clbn - Nuclear export mediator factor NEMF homolog; Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. Clbn/NEMF is responsible for selective recognition of stalled 60S subunits by recognizing an exposed, nascent chain-conjugated tRNA moiety. Clbn/NEMF is important for the stable association of l(3)76BDr/LTN1 to the complex (By similarity). Plays a role in regulating nuclear transport possibly through directly binding to both emb and cargo proteins.
[a.k.a. FBgn0259152, Clbn-PC, Clbn-PB,
7227.FBpp0290493
]