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Su(z)12 | Polycomb protein Su(z)12; Polycomb group (PcG) protein. While PcG proteins are generally required to maintain the transcriptionally repressive state of homeotic genes throughout development, this protein is specifically required during the first 6 hours of embryogenesis to establish the repressed state. Component of the Esc/E(z) complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The Esc/E(z) complex is necessary but not sufficient for the repression of homeotic target genes, suggesting that [...] (900 aa) | ||||
Arl6 | ADP ribosylation factor-like 6, isoform A; GTP binding; GTPase activity. It is involved in the biological process described with: vesicle-mediated transport; intracellular protein transport; intracellular transport; cilium assembly; protein localization to cilium; Belongs to the small GTPase superfamily. Arf family. (202 aa) |