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The following proteins in
Drosophila melanogaster
appear to match your input.
Please review the list, then click 'Continue' to proceed.
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⤓ Mapping
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1) '7227.FBpp0075510':
upSET - UpSET, isoform A; upSET (upSET) encodes a Polycomb/Trithorax-type global transcriptional regulator. It is recruited to active and inducible genes where it restricts chromatin accessibility and histone acetylation to promoter regions. upSET loss produces female sterility.
[a.k.a. FBgn0036398, upSET-PA, upSET-PB,
7227.FBpp0075510
]
2) '7227.FBpp0080787':
Top3alpha - DNA topoisomerase 3-alpha; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)- enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand than undergoes passage around the unbroken strand thus removing DNA supercoils [...]
[a.k.a. FBgn0040268, Top3alpha-PA, FBtr0081246,
7227.FBpp0080787
]