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Jarid2 | Jumonji, AT rich interactive domain 2 (Jarid2) encodes a nuclear protein that functions as a DNA-binding transcriptional repressor. It functions as a scaffold for the recruitment of various complexes, including Polycomb repressive complex 2. It is involved in intestinal stem proliferation and differentiation. (2351 aa) | ||||
PK2-R1 | Pyrokinin 2 receptor 1 (PK2-R1) encodes a G protein-coupled receptor that binds the neuropeptide encoded by Hug with high affinity. After binding, a second messenger cascade is initiated in cells that are target for the product of Hug (mainly neurons of the central nervous system). (660 aa) |