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Elba3 | Early boundary activity protein 3; The heterotrimeric Elba complex is required for chromatin domain boundary function during early embryogenesis. It binds to a 8-bp sequence 5'-CCAATAAG-3' in the Fab-7 insulator or boundary element in the bithorax complex and contributes to its insulator or boundary activity. Elba3 lacks DNA-binding activity and plays the role of an adapter protein, bringing Elba1 and 2 together, thereby establishing a complex that recognizes the asymmetric sequence motif through the BEN domains of Elba1 and 2. (379 aa) | ||||
Tollo | Toll-like receptor Tollo; Toll-related receptor. Probably specific to larval innate immunity. Involved in the tracheal immune response of larvae to Gram-negative and perhaps Gram-positive bacteria; upon infection it negatively regulates the immune deficiency (Imd) signaling cascade specifically in the respiratory epithelium to prevent the overexpression of antimicrobial peptides (AMP). Involved in the NF-kappa-B-dependent apoptosis of unfit cells during cell competition. Involved in neuron-specific glycosylation. Positively controls the neuromuscular junction (NMJ) growth in presynapti [...] (1346 aa) |