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The following proteins in
Drosophila melanogaster
appear to match your input.
Please review the list, then click 'Continue' to proceed.
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⤓ Mapping
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1) '7227.FBpp0077377':
Elba2 - Early boundary activity protein 2; The heterotrimeric Elba complex is required for chromatin domain boundary function during early embryogenesis. It binds to a 8-bp sequence 5'-CCAATAAG-3' in the Fab-7 insulator or boundary element in the bithorax complex and contributes to its insulator or boundary activity. Elba2 can act as a transcriptional repressor and binds the palindromic sequence 5'-CCAATTGG-3' to mediate transcriptional repression.
[a.k.a. FBgn0031435, Elba2-PA, dme:Dmel_CG9883,
7227.FBpp0077377
]
2) 'grnd':
grnd
- Grindelwald (
grnd
) encodes a receptor of the TNF superfamily ligand encoded by egr, which activates the intracellular JNK pathway. It is involved in apoptosis and neoplastic growth.
egr - Protein eiger, membrane form; Cytokine which acts as a ligand for wgn. Also acts as a ligand for
grnd
. Induces apoptosis by triggering JNK signaling. Required for JNK-dependent non-autonomous apoptosis through release from apoptotic cells and activation of apoptosis in neighboring cells. Required for JNK-independent damage-induced apoptosis in the embryonic central nervous system through regulation of the pro-apoptotic gene hid. Involved in the innate immune response to extracellular pathogens. Plays a role in the melanization immune response through its involvement in the rupture of c [...]
[a.k.a. FBgn0033483, egr-PB, egr-PA]