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Dref | DNA replication-related element factor (Dref) encodes a BED finger-type transcription factor that binds to the DRE sequence (TATCGATA). The Dref product is involved in tumor suppressor, TOR, JNK and EGFR signalling pathways. It also plays a role in chromatin organization including insulator function, chromatin remodeling, and telomere maintenance. (709 aa) | ||||
IntS10 | Integrator complex subunit 10; Component of the Integrator complex, a complex involved in the transcription of small nuclear RNAs (snRNA) and their 3'-box- dependent processing. May be involved in the 3'-end processing of the spliceosomal snRNAs U1, U2, U4 and U5 but is probably not essential for 3'-end processing of the snRNA U7. (631 aa) |