Your Input: | |||||
Su(H) | Suppressor of hairless protein; Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Binds directly the 5'-GTGRGAR-3' DNA consensus sequence, which is present in the regulatory region of several genes. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some Notch protein, it acts as a transcriptional activator that activates transcription of Notch target genes. Required for transcription of Sim. Spec [...] (594 aa) | ||||
c(2)M | Crossover suppressor on 2 of Manheim (c(2)M) encodes a Kleisin family member in the cohesin proteins. It interacts with cohesins, such as the products of SMC1 and SMC3, to promote synaptonemal complex assembly in female meiosis. (570 aa) |