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The following proteins in
Drosophila melanogaster
appear to match your input.
Please review the list, then click 'Continue' to proceed.
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1) '7227.FBpp0080261':
Su(H) - Suppressor of hairless protein; Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Binds directly the 5'-GTGRGAR-3' DNA consensus sequence, which is present in the regulatory region of several genes. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some Notch protein, it acts as a transcriptional activator that activates transcription of Notch target genes. Required for transcription of Sim. Spec [...]
[a.k.a. FBgn0004837, Su(H)-PA, Su(H)-PC,
7227.FBpp0080261
]
2) '7227.FBpp0111630':
Snoo - Sno oncogene (Snoo) encodes a protein that belongs to the highly conserved Sno/Ski family of Smad binding proteins. It specifically binds the product of Med and switches its affinity from the products of Mad to Smox, resulting in antagonism of the product of dpp and facilitation of Activin signaling. Snoo overexpression antagonizes both pathways.
[a.k.a. FBgn0085450, Snoo-PB, Snoo-PG,
7227.FBpp0111630
]