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The following proteins in
Drosophila melanogaster
appear to match your input.
Please review the list, then click 'Continue' to proceed.
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1) '7227.FBpp0080261':
Su(H) - Suppressor of hairless protein; Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Binds directly the 5'-GTGRGAR-3' DNA consensus sequence, which is present in the regulatory region of several genes. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some Notch protein, it acts as a transcriptional activator that activates transcription of Notch target genes. Required for transcription of Sim. Spec [...]
[a.k.a. FBgn0004837, Su(H)-PA, Su(H)-PC,
7227.FBpp0080261
]
2) '7227.FBpp0290765':
sbb - Scribbler, isoform J; Scribbler (sbb) encodes a transcriptional co-regulator that acts mainly as a co-repressor. It interacts physically and genetically with the product of Gug and is used by the repressor encoded by tll in early embryos. It regulates larval behavior, photoreceptor axon target choice, and functions downstream of Hedgehog signaling.
[a.k.a. FBgn0285917, sbb-PG, sbb-PH,
7227.FBpp0290765
]