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msl-1 | Protein male-specific lethal-1; The Msl proteins are essential for elevating transcription of the single X chromosome in the male (X chromosome dosage compensation). Msl-1 is a pioneer protein. Mle, msl-1 and msl-3 are colocalized on the X chromosome. Each of the MSL proteins requires all the other MSLs for wild-type X-chromosome binding. In complex with msl-2, promotes ubiquitination of histone H2B. (1039 aa) | ||||
RanBP3 | Ran binding protein 3 (RanBP3) encodes a chromosome region maintenance 1 (CRM1) cofactor involved in the export of proteins from the nucleus. It negatively regulates Wnt signalling. (449 aa) |