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bcd | Homeotic protein bicoid; Segment polarity protein that provides positional cues for the development of head and thoracic segments. Regulates the expression of zygotic genes, possibly through its homeodomain, and inhibits the activity of other maternal gene products. May also bind RNA. Interacts with Bin1 to repress transcription of bicoid target genes in the anterior tip of the embryo; a process known as retraction. (494 aa) | ||||
dy | LP20007p; Dusky (dy) encodes a membrane-anchored protein of the zona pellucida domain protein familiy. Along with the homologous gene m, it regulates epidermal cell size/shape changes during wing morphogenesis. It also functions to remodel epidermal cell shape during embryonic and later developmental stages, through interactions with the extracellular matrix. (699 aa) |