Your Input: | |||||
zen | Protein zerknuellt 1; Required for the differentiation of the dorsal-ventral pattern, and does not appear to be involved in the process of segmentation. (353 aa) | ||||
Topors | E3 ubiquitin-protein ligase Topors; Functions as a ubiquitin-protein E3 ligase. Negatively regulates the transcriptional repressor h/hairy by promoting its ubiquitination and subsequent degradation. Also directs the nuclear organization of the gypsy chromatin insulator. Chromatin insulators are regulatory elements which establish independent domains of transcriptional activity within eukaryotic genomes. Insulators have two defining properties; they can block the communication between an enhancer and a promoter when placed between them, and can also buffer transgenes from position effec [...] (1038 aa) |