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Mcm2 | DNA replication licensing factor Mcm2; Acts as component of the Mcm2-7 complex (Mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the Mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (887 aa) | ||||
morgue | Modifier of rpr and grim, ubiquitously expressed (morgue) encodes an F box/ubiquitin conjugase domain protein. It regulates cell death by controlling the levels of the apoptosis inhibitor encoded by Diap1. (491 aa) |