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Scm | Polycomb protein Scm; Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via the methylation of histones, rendering chromatin heritably changed in its expressibility; Belongs to the SCM family. (877 aa) | ||||
BigH1 | Histone H1 variant BigH1 (BigH1) encodes a germline linker histone H1 variant that is retained in the early embryo until cellularization. It is required for gametogenesis and to maintain silencing of the zygotic genome during early embryogenesis. (353 aa) |