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rump | Rumpelstiltskin, isoform A; Rumpelstiltskin (rump) encodes the Drosophila hnRNP M homolog. It binds to nos and osk mRNAs and plays a role in mRNA localization to the germ plasm by diffusion/entrapment during late stages of oogenesis. It also binds to exonic splicing enhancers on pre-mRNA targets, implicating it as a splicing factor. (632 aa) | ||||
Rad1 | DNA repair protein Rad1; Radiation insensitive 1 (Rad1) encodes a protein that together with proteins encoded by Rad9 and Hus1-like form the 9-1-1 checkpoint protein complex. This complex plays a central role in the DNA damage-induced checkpoint response. (274 aa) |