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Su(var)3-7 | Suppressor of variegation 3-7 (Su(var)3-7) encodes a protein associated with heterochromatin. Increasing the amount of the product of Su(var)3-7 triggers heterochromatin expansion and epigenetic gene silencing. (1250 aa) | ||||
Zwilch | Protein zwilch; Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin, Mad2 complexes and spindly/CG15415 onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the RZZ complex. Failure to assemble the complex due to the absence of any one of its components, results in the incorrect redistribution of the remaining components to diverse membrane compartments ; Belongs to the ZWILCH family. (641 aa) |