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trx | Histone-lysine N-methyltransferase trithorax; Histone methyltransferase that trimethylates 'Lys-9' of histone H3 (H3K9me3). H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional activation. Functions in segment determination through interaction with genes of bithorax (BX-C) and antennapedia (ANT-C) complexes. Acts as an activator of BX-C. Involved in the very early regulation of homeotic genes expressed only in the posterior region of the embryo. (3726 aa) | ||||
ppk6 | Pickpocket 6 (ppk6) encodes a member of the DEG/ENaC family, whose members act as non-voltage-gated cation channels. DEG/ENaC family members have been implicated in the maintenance of sodium gradients across epithelial membranes, as well as in diverse sensory modalities, which include gustatory chemosensation, mechanosensation, hygrosensation, and nociception; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (498 aa) |