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Oga | O-GlcNAcase (Oga) encodes a protein that, together with the product of sxc, is responsible for O-GlcNAcylation. O-GlcNAcylation is a dynamic post-translational modification that modifies serine and threonine residues of proteins, and plays important roles in biological functions such as metabolism and neurodegeneration. (1019 aa) | ||||
IntS3 | Integrator complex subunit 3; Component of the Integrator complex, a complex involved in the transcription of small nuclear RNAs (snRNA) and their 3'-box- dependent processing. However this subunit is not essential for the 3'-end processing of the snRNA U7 and the spliceosomal snRNAs U1, U2, U4 and U5. Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (By similarity). (1068 aa) |