2 items (Drosophila melanogaster) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	tin	Muscle-specific homeobox protein tinman; Required for the development of heart and visceral muscle; for the formation of somatic muscles. Has a crucial function in the early mesodermal subdivisions. (416 aa)
	Sas10	Something about silencing 10 (Sas10) encodes a protein belonging to the SAS10 family. It might be a substrate of the RNA deaminase encoded by Adar, which shows an adenosine to inosine (A-to-I) deaminase activity in pre-mRNA transcripts. The noncoding strand of the adjacent gene, Rnp4F, reads through to form a duplex with Sas10 transcripts at their 3'-end to target both transcripts for promiscuous A-to-I editing and degradation. (428 aa)

Your Current Organism:

Drosophila melanogaster

NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly