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HP1c HP1c miple2 miple2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HP1cHeterochromatin Protein 1c (HP1c) encodes a chromatin binding protein that is involved in telomere capping and transcription regulation and interacts with the zinc-finger proteins encoded by woc and row. (237 aa)
miple2Midkine and pleiotrophin 2 (miple2) encodes a small secreted protein that binds Heparin and is closely related at the amino acid sequence to the product of miple1. It is strongly expressed in the developing endoderm. (282 aa)
Your Current Organism:
Drosophila melanogaster
NCBI taxonomy Id: 7227
Other names: D. melanogaster, Diptera sp. DNAS-2A9-224646, Sophophora melanogaster, fruit fly
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