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Nup98-96 | Nuclear pore complex protein Nup98-Nup96; Part of the nuclear pore complex (NPC). Required for MAD import as part of the Nup107-160 complex and required for nuclear export of Moe probably via its association with Rae1. Plays a role in nuclear mRNA export. Promotes cell antiviral response by upregulating FoxK-dependent antiviral gene transcription. In germline stem cells, involved in their maintenance and division together with the TGF-Beta and EGFR signaling pathways. In larval lymph glands, has a role in the maintenance of hematopoiesis by regulating Pvr expression. [Nuclear pore comp [...] (1960 aa) | ||||
arr | Low-density lipoprotein receptor-related protein; Arrow (arr) encodes a type I trans-membrane protein and functions as an obligate co-receptor with the product of fz for the ligand encoded by wg in the canonical Wnt signaling pathway. The product of arr is involved in developmental patterning, cell survival and growth regulation; Belongs to the LDLR family. (1678 aa) |