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Nup98-96 | Nuclear pore complex protein Nup98-Nup96; Part of the nuclear pore complex (NPC). Required for MAD import as part of the Nup107-160 complex and required for nuclear export of Moe probably via its association with Rae1. Plays a role in nuclear mRNA export. Promotes cell antiviral response by upregulating FoxK-dependent antiviral gene transcription. In germline stem cells, involved in their maintenance and division together with the TGF-Beta and EGFR signaling pathways. In larval lymph glands, has a role in the maintenance of hematopoiesis by regulating Pvr expression. [Nuclear pore comp [...] (1960 aa) | ||||
Fkbp14 | Peptidylprolyl isomerase; FK506-binding protein 14 (Fkbp14) encodes an ER resident protein and a member of the large FKBP family of immunophilins. It plays an essential role in development, including stabilizing the protein encoded by Psn in the ER. Fkbp14 mutants genetically interact with components of the Notch pathway. (220 aa) |