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Sce | E3 ubiquitin-protein ligase RING1; E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-118' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-118' ubiquitination gives a specific tag for epigenetic transcriptional repression. Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. PcG [...] (435 aa) | ||||
zyd | Zydeco, isoform F; Zydeco (zyd) encodes a potassium-dependent sodium/calcium exchanger found in cortex glia. It is thought to serve as a key calcium export pathway to control calcium oscillations that occur in membrane microdomains of the glial cell; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (542 aa) |