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mle | Dosage compensation regulator; Required in males for dosage compensation of X chromosome linked genes. Mle, msl-1 and msl-3 are colocalized on X chromosome. Each of the msl proteins requires all the other msls for wild-type X- chromosome binding. Probably unwinds double-stranded DNA and RNA in a 3' to 5' direction; Belongs to the DEAD box helicase family. DEAH subfamily. (1293 aa) | ||||
Ntf-2 | Nuclear transport factor-2 (Ntf-2) is an essential gene regulating nuclear import. It encodes a protein that binds to the nuclear pore protein encoded by DCTN4-p62 and to the product of Ran and regulates the nuclear import of nuclear localization signal containing proteins. (130 aa) |