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Iswi | Chromatin-remodeling complex ATPase chain Iswi; Energy-transducing component of the chromatin-remodeling complexes NURF (nucleosome-remodeling factor), ACF (ATP-utilizing chromatin assembly and remodeling factor), and CHRAC (chromatin accessibility complex). NURF catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin. It is required for homeotic gene expression, proper larval blood cell development, normal male X chromosome morphology, ecdysteroid signaling and metamorphosis. (1027 aa) | ||||
ovo | Transcriptional activator shavenbaby; Transcriptional regulator with essential functions in the germline and soma. Plays an essential role in regulating the formation of apical cell extensions such as denticles and aristae, and initiating cytoskeletal remodeling during epidermal differentiation. [Transcriptional activator shavenbaby]: Transcriptional activator which initiates trichome development and also promotes tarsal joint development. Has an essential somatic role regulating the tal-dependent formation of trichomes, and initiating cytoskeletal remodeling during epidermal different [...] (1351 aa) |