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Kdm4A | Lysine (K)-specific demethylase 4A (Kdm4A) encodes a histone lysine demethylase that catalyzes removal of methyl groups using alpha-ketoglutarate as a cofactor. It demethylates H3K36me3 and is implicated in the demethylation of H3K9me3 and H3K56me3. Its roles include transcription, DNA repair, and heterochromatin silencing. (495 aa) | ||||
bw | Brown (bw) encodes a member of the traffic ATPase (or ABC) family of membrane transporters. It is believed to heterodimerize with the product of w. bw and w are necessary to import guanine, a precursor for the red pteridine pigments, into pigment cells of the eyes, Malpighian tubules and testis sheath. (675 aa) |