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ey | Paired box protein Pax-6; Eyeless (ey) encodes a transcription factor that is involved in eye development as part of the retinal determination gene network, and contributes to brain formation. (898 aa) | ||||
cwo | Transcription factor cwo; Plays a role in the regulation of circadian rhythms. Transcriptional repressor which inhibits Clock-mediated transcriptional activation by binding to E boxes in the promoters of Clock target genes and repressing their transcription. E box binding activity is time- dependent with higher binding activity seen in the early morning (zeitgeber time 2) than early evening (zeitgeber time 14) and is dependent on the presence of the circadian protein per. It is likely that per binds to Clock-cycle heterodimers, reducing their affinity for E box binding and allowing cwo [...] (698 aa) |