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Sgf11 | SAGA-associated factor 11 homolog; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Binds independently on SAGA to promoters in an RNA- dependent manner. Bind [...] (196 aa) | ||||
SuUR | Protein suppressor of underreplication; Required for underreplication of DNA, which is found in many late replicating euchromatic regions of salivary gland polytene chromosomes. Functions by promoting the localization and retention of Rif1 to active DNA replication forks where Rif1 inhibits replication fork progression. Controls chromatin organization in polytene chromosomes. (962 aa) |