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The following proteins in
Drosophila melanogaster
appear to match your input.
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⤓ Mapping
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1) '7227.FBpp0288697':
yki - Transcriptional coactivator yorkie; Transcriptional coactivator which is the critical downstream regulatory target in the Hippo/SWH (Sav/Wts/Hpo) signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein Hippo (Hpo), in complex with its regulatory protein Salvador (Sav), phosphorylates and activates Warts (Wts) in complex with its regulatory protein Mats, which in turn phosphorylates and inactivates the Yorkie (Yki) oncoprotein. The Hippo/ [...]
[a.k.a. FBgn0034970, yki-PH, yki-PD,
7227.FBpp0288697
]
2) '7227.FBpp0082158':
Spc25 - Kinetochore protein Spc25; Acts as a component of the essential kinetochore-associated Ndc80 complex, which is required for chromosome segregation and spindle checkpoint activity during meiosis and mitosis. Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore. Participates in SAC signaling that responds specifically to disruptions in spindle microtubule dynamics. The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing [...]
[a.k.a. FBgn0087021, Spc25-PA, CG7242,
7227.FBpp0082158
]