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The following proteins in
Drosophila melanogaster
appear to match your input.
Please review the list, then click 'Continue' to proceed.
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1) '7227.FBpp0288697':
yki - Transcriptional coactivator yorkie; Transcriptional coactivator which is the critical downstream regulatory target in the Hippo/SWH (Sav/Wts/Hpo) signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein Hippo (Hpo), in complex with its regulatory protein Salvador (Sav), phosphorylates and activates Warts (Wts) in complex with its regulatory protein Mats, which in turn phosphorylates and inactivates the Yorkie (Yki) oncoprotein. The Hippo/ [...]
[a.k.a. FBgn0034970, yki-PH, yki-PD,
7227.FBpp0288697
]
2) '7227.FBpp0305817':
RhoGAPp190 - Rho GTPase-activating protein 190; GTPase-activating protein (GAP) for RhoA/Rho1 that plays an essential role in the stability of dorsal branches of mushroom body (MB) neurons. The MB neurons are the center for olfactory learning and memory. Acts by converting RhoA/Rho1 to an inactive GDP-bound state, leading to repress the RhoA/Rho1-Drok-MRLC signaling pathway thereby maintaining axon branch stability.
[a.k.a. FBgn0026375, RhoGAPp190-PE, RhoGAPp190-PC,
7227.FBpp0305817
]